A cell line is a kind of cell culture where cells proliferate and multiply in the apt growth environment. Different cell lines are made from distinct cells. Cell lines facilitate step-by-step alterations in the genetic makeup, physiology, and structure of cells under a customized surrounding. Cell line development has a wide range of applications in recombinant protein & antibody production, gene functional, and drug screening studies using stable cell lines. The process of building stable cell lines includes quantification and screening of high pressuring clones, transfecting the selected host cells with plasmids, and validation of proteins.
Technological advancements in the pharmaceutical and biological industry are one of the major factors fueling the growth of the global cell line development services market. There is an increasing need for massive vaccine production owing to the unprecedented outbreak of Covid-19 all across the globe. Vaccination is the only way to treat coronavirus infection, thereby it is likely to bolster the growth of the global cell line development services market vigorously in the forthcoming years. The increasing demand for monoclonal antibodies and biosimilars is likely to provide enough thrust for significant growth due to the fact that governments are making every effort to overcome the growing burden of chronic diseases. There is a significant growth in the utilization of recombinant cell lines for lowering the cost of biopharmaceutical protein production. Moreover, these are also widely utilized in the diagnostic process of diseases like cancer and autoimmune disorders.
The global cell line development services market can be segmented into application, source, product, and region.
By application, the market can be segmented into drug discovery, research, toxicity testing, tissue engineering & regenerative medicine, bioproduction, and others.
By source, the market can be segmented into the insect, mammalian, and others.
By product, the market can be segmented into reagents & media, equipment, and others.
North America accounts for the largest share in the global cell line development services market due to the presence of well-established healthcare infrastructure. Moreover, the growing initiatives from the government to provide advanced care services to the patients and get rid of the growing prevalence of chronic diseases like cancer and diabetes will further fuel the growth of the regional market in forthcoming years.
Some of the significant players in the global cell line development services market are Sartorius AG, Aragen Bioscience, GE Healthcare, Thermo Fisher Scientific, WuXi Biologics, Sphere Fluidics Limited, Solentim Ltd., ATCC, Lonza, Selexis SA, and Merck KGaA. To cite, CBMG partnered with GE Healthcare in 2017. The deal is likely to start the manufacturing of stem cells in the company that are widely utilized in cell line development.